Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018747 | 0.84 | CYP11B1 (0.31) | — | |
| SCHEMBL4181101 | 0.82 | — | — | |
| SCHEMBL4025845 | 0.77 | KDM4E (0.32) | KCNN4KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL4018376 | 0.75 | CYP19A1 (0.37) | KCNN4KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8188378 | 0.67 | KMT2A (0.46) | KCNN4KCNA3MEN1KMT2A | |
| SCHEMBL15649336 | 0.65 | BRD4 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL5447440 | 0.65 | CYP19A1 (0.36) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3743240 | 0.64 | CYP11B1 (0.43) | KCNN4KCNA3MEN1MAPTKMT2A | |
| SCHEMBL6366761 | 0.62 | MEN1 (0.51) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL3855549 | 0.61 | PDE10A (0.39) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |