Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018376 | 0.78 | CYP19A1 (0.37) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL3500675 | 0.78 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL4018934 | 0.77 | PDE2A (0.31) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL4018747 | 0.76 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL4181101 | 0.74 | — | — | |
| SCHEMBL8188378 | 0.70 | KMT2A (0.46) | MEN1KMT2ACYP11B1CYP11B2KCNN4 | |
| SCHEMBL1423935 | 0.68 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL5447440 | 0.68 | CYP19A1 (0.36) | KDM4EMEN1ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL8022922 | 0.68 | NOTUM (0.36) | CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL10676751 | 0.65 | NOTUM (0.36) | KDM4EMEN1ALDH1A1KMT2ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |