Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22199369 | 1.00 | TSHR (0.40) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL19228952 | 1.00 | TSHR (0.40) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL19228957 | 1.00 | TSHR (0.40) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL19228949 | 1.00 | TSHR (0.40) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL10089720 | 1.00 | TSHR (0.40) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL10138522 | 1.00 | TSHR (0.40) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL10101994 | 1.00 | TSHR (0.40) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL935503 | 0.95 | — | — | |
| SCHEMBL26205670 | 0.90 | TSHR (0.47) | TSHRMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL22589673 | 0.86 | TSHR (0.48) | TSHRMEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |