SCHEMBL10101994

SCHEMBL10101994

C#CCOCCOCCOCCOCCC

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.32
THRB P10828 1/20 0.30
HTT P42858 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40194 1.00 TSHR (0.40) TSHRMEN1KMT2AALDH1A1HSD17B10
SCHEMBL22199369 1.00 TSHR (0.40) TSHRMEN1KMT2AALDH1A1HSD17B10
SCHEMBL19228952 1.00 TSHR (0.40) TSHRMEN1KMT2AALDH1A1HSD17B10
SCHEMBL19228957 1.00 TSHR (0.40) TSHRMEN1KMT2AALDH1A1HSD17B10
SCHEMBL19228949 1.00 TSHR (0.40) TSHRMEN1KMT2AALDH1A1HSD17B10
SCHEMBL10089720 1.00 TSHR (0.40) TSHRMEN1KMT2AALDH1A1HSD17B10
SCHEMBL10138522 1.00 TSHR (0.40) TSHRMEN1KMT2AALDH1A1HSD17B10
SCHEMBL935503 0.95
SCHEMBL26205670 0.90 TSHR (0.47) TSHRMEN1KMT2AALDH1A1HSD17B10
SCHEMBL22589673 0.86 TSHR (0.48) TSHRMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-20230287030-A1 Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions THE GENERAL HOSPITAL CORPORATION 2023-09-14 US disclosed
US-10188136-B2 Hydrophobin mimics: process for preparation thereof INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IN) 2019-01-29 US disclosed
US-20170362266-A1 Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions THE GENERAL HOSPITAL CORPORATION 2017-12-21 US disclosed
US-20170231260-A1 HYDROPHOBIN MIMICS: PROCESS FOR PREPARATION THEREOF INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IN) 2017-08-17 US disclosed
US-20170231260-A1 HYDROPHOBIN MIMICS: PROCESS FOR PREPARATION THEREOF INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IN) 2017-08-17 US disclosed
US-20120046461-A1 STEROIDAL ANTI-HORMONE HYBRIDS NORTHEASTERN UNIVERSITY (US) 2012-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A TSHR 2184/4885MEN1 3968/4885KMT2A 4104/4885
US-20170231260-A1 HYDROPHOBIN MIMICS: PROCESS FOR PREPARATION THEREOF CHN2, NEFM, HGF TSHR 4020/4885MEN1 317/4885KMT2A 4097/4885
US-20120046461-A1 STEROIDAL ANTI-HORMONE HYBRIDS ESRRA, ESRRB, NR5A1 TSHR 1263/4885MEN1 4158/4885KMT2A 3900/4885
US-20170362266-A1 Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions GALNT14, NEU4, CSGALNACT1 TSHR 3743/4885MEN1 4631/4885KMT2A 3703/4885
US-11833213-B2 Compositions and methods for the treatment of viral infections FCGR3B, ALB, FCGR1A TSHR 2184/4885MEN1 3968/4885KMT2A 4104/4885
US-20230287030-A1 Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions GALNT14, NEU4, CSGALNACT1 TSHR 3743/4885MEN1 4631/4885KMT2A 3703/4885
US-10188136-B2 Hydrophobin mimics: process for preparation thereof CHN2, NEFM, HGF TSHR 4020/4885MEN1 317/4885KMT2A 4097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.