Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.74 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.61 |
| ▸ | HTR3B | O95264 | 2/20 | 0.61 |
| ▸ | HTR3A | P46098 | 2/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.61 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.57 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4801101 | 0.83 | TAAR1 (0.63) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9314304 | 0.83 | TAAR1 (0.63) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9595523 | 0.80 | GRIN2B (0.57) | TAAR1GRIN2BGRIN1CYP1A2CYP2D6 | |
| SCHEMBL9595519 | 0.80 | GRIN2B (0.57) | TAAR1GRIN2BGRIN1CYP1A2CYP2D6 | |
| SCHEMBL1737052 | 0.78 | GRIN1 (0.62) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9667523 | 0.77 | TAAR1 (0.71) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4316027 | 0.77 | TAAR1 (0.55) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL538276 | 0.74 | HTR3E (0.96) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7765310 | 0.74 | TAAR1 (0.53) | TAAR1GRIN2BCYP1A2CYP2D6THPO | |
| SCHEMBL7765314 | 0.74 | TAAR1 (0.53) | TAAR1GRIN2BCYP1A2CYP2D6THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009087395-A1 | WEIGHT REDUCING COMPOUNDS | UNIVERSITY OF STRATHCLYDE (GB) | 2009-07-16 | — | — | WO | disclosed |