Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313348 | 0.85 | KMT2A (0.40) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL1528022 | 0.80 | KMT2A (0.44) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL27544681 | 0.80 | KMT2A (0.41) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL8806580 | 0.80 | KMT2A (0.44) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL4759513 | 0.78 | KMT2A (0.42) | KMT2AMEN1CYP11B1CYP11B2 | |
| SCHEMBL8806973 | 0.78 | KMT2A (0.42) | KMT2AMEN1CYP11B1CYP11B2 | |
| SCHEMBL9229669 | 0.78 | KMT2A (0.39) | KMT2AMEN1CYP11B1CYP11B2 | |
| SCHEMBL5319750 | 0.77 | MEN1 (0.41) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4759621 | 0.77 | KMT2A (0.38) | KMT2AMEN1CYP11B1CYP11B2KCNA3 | |
| SCHEMBL8188378 | 0.76 | KMT2A (0.46) | KMT2AMEN1CYP11B1CYP11B2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |