Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019670 | 0.85 | KMT2A (0.38) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL6467815 | 0.79 | KMT2A (0.43) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL6948425 | 0.79 | KMT2A (0.43) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL647893 | 0.79 | KMT2A (0.46) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL5327785 | 0.79 | KMT2A (0.43) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL8188378 | 0.79 | KMT2A (0.46) | KMT2AMEN1CYP11B1CYP11B2KCNA3 | |
| SCHEMBL1845371 | 0.79 | KMT2A (0.43) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL1528204 | 0.78 | KMT2A (0.40) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL1528022 | 0.76 | KMT2A (0.44) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL27544681 | 0.76 | KMT2A (0.41) | KMT2AMEN1CYP11B1CYP11B2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286721-A | Antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
| WO-1992006978-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-30 | — | — | WO | disclosed |