Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023934 | 0.85 | BCHE (0.67) | BCHEHTR2A | |
| SCHEMBL4026270 | 0.85 | BCHE (0.64) | BCHEHTR2ANPC1MLNRNR1I2 | |
| SCHEMBL4023951 | 0.85 | BCHE (0.64) | BCHEHTR2ANPC1MLNRNR1I2 | |
| SCHEMBL4021697 | 0.84 | BCHE (0.65) | BCHEHTR2ANPC1MLNRNR1I2 | |
| SCHEMBL4023303 | 0.84 | BCHE (0.65) | BCHEHTR2ANPC1MLNRNR1I2 | |
| SCHEMBL14383256 | 0.80 | BCHE (1.00) | BCHEHTR2ANPC1MLNRNR1I2 | |
| SCHEMBL4022560 | 0.77 | BCHE (0.56) | BCHEHTR2ANPC1MLNRNR1I2 | |
| SCHEMBL4023903 | 0.77 | BCHE (0.64) | BCHEHTR2ANPC1MLNRNR1I2 | |
| SCHEMBL4024417 | 0.77 | BCHE (0.64) | BCHEHTR2ANPC1MLNRNR1I2 | |
| SCHEMBL9563324 | 0.77 | BCHE (0.69) | BCHEPARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446400-B1 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC NARA CO LTD (KR) | 2009-01-28 | — | — | EP | claimed |
| US-7288552-B2 | Piperidine derivatives, process for preparation thereof, and pharmaceutical composition for alzheimer's disease containing the same | STC NARA CO., LTD. (KR) | 2007-10-30 | — | — | US | claimed |
| EP-1446400-A4 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC NARA CO LTD (KR) | 2005-06-01 | — | — | EP | claimed |
| US-20050043316-A1 | Piperidine derivatives, process for preparation thereof, and pharmaceutical composition for alzheimer's disease containing the same | STC NARA CO., LTD. (KR) | 2005-02-24 | — | — | US | claimed |
| EP-1446400-A1 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC Nara Co. Ltd. (KR) | 2004-08-18 | — | — | EP | claimed |
| WO-2003033489-A1 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC NARA CO., LTD. (KR) | 2003-04-24 | — | — | WO | claimed |
| EP-1446400-B1 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC NARA CO LTD (KR) | 2009-01-28 | — | — | EP | disclosed |
| US-7288552-B2 | Piperidine derivatives, process for preparation thereof, and pharmaceutical composition for alzheimer's disease containing the same | STC NARA CO., LTD. (KR) | 2007-10-30 | — | — | US | disclosed |
| EP-1446400-A4 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC NARA CO LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| US-20050043316-A1 | Piperidine derivatives, process for preparation thereof, and pharmaceutical composition for alzheimer's disease containing the same | STC NARA CO., LTD. (KR) | 2005-02-24 | — | — | US | disclosed |
| EP-1446400-A1 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC Nara Co. Ltd. (KR) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003033489-A1 | PIPERIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ALZHEIMER'S DISEASE CONTAINING THE SAME | STC NARA CO., LTD. (KR) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043316-A1 | Piperidine derivatives, process for preparation thereof, and pharmaceutical composition for alzheimer's disease containing the same | APP, ACHE, PSEN1 | BCHE 7/4885HTR2A 1505/4885NPC1 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.