Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SI | P14410 | 3/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28853261 | 0.85 | MEN1 (0.56) | GPR84FFAR1KMT2AMEN1NOD2 | |
| SCHEMBL8234032 | 0.80 | GPR84 (0.53) | GPR84FFAR1PBRM1KMT2AMEN1 | |
| SCHEMBL8133070 | 0.79 | GPR84 (0.45) | GPR84FFAR1PBRM1KMT2AMEN1 | |
| SCHEMBL5645874 | 0.78 | GPR84 (0.62) | GPR84FFAR1KMT2AMEN1HTR2A | |
| SCHEMBL27419501 | 0.78 | KMT2A (0.50) | GPR84FFAR1PBRM1KMT2AMEN1 | |
| SCHEMBL7615301 | 0.77 | GPR84 (0.67) | GPR84FFAR1KMT2AMEN1HTR2A | |
| SCHEMBL5513681 | 0.77 | GPR84 (0.67) | GPR84FFAR1PBRM1KMT2AMEN1 | |
| SCHEMBL18135253 | 0.76 | GPR84 (0.53) | GPR84FFAR1PBRM1KMT2AMEN1 | |
| SCHEMBL6283244 | 0.76 | GPR84 (0.59) | GPR84FFAR1KMT2AMEN1NOD2 | |
| SCHEMBL27514167 | 0.76 | GPR84 (0.61) | GPR84FFAR1PBRM1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940787-A4 | NOVEL IDO INHIBITORS AND METHODS OF USE THEREOF | LANKENAU INST MEDICAL RES (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-1940787-A1 | NOVEL IDO INHIBITORS AND METHODS OF USE THEREOF | Lankenau Institute for Medical Research (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007050963-A1 | NOVEL IDO INHIBITORS AND METHODS OF USE THEREOF | LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) | 2007-05-03 | — | — | WO | disclosed |