Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
| ▸ | PSD | A5PKW4 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020354 | 1.00 | TRPV1 (0.41) | TRPV1TYMSPSDCNR1GABRA1 | |
| SCHEMBL13747129 | 0.82 | TYMS (0.38) | TRPV1TYMSPSDCNR1GABRA1 | |
| SCHEMBL13746236 | 0.80 | TYMS (0.41) | TRPV1TYMSPSDCNR1GABRA1 | |
| SCHEMBL13746305 | 0.80 | TYMS (0.41) | TRPV1TYMSPSDCNR1GABRA1 | |
| SCHEMBL13746410 | 0.76 | TYMS (0.39) | TRPV1TYMSPSDCNR1PDE2A | |
| SCHEMBL13746006 | 0.76 | TYMS (0.39) | TRPV1TYMSPSDCNR1GABRA1 | |
| SCHEMBL13746092 | 0.74 | PSD (0.38) | TRPV1TYMSPSDCNR1GABRA1 | |
| SCHEMBL4192359 | 0.74 | PSD (0.38) | TRPV1TYMSPSDCNR1GABRA1 | |
| SCHEMBL13746104 | 0.73 | TYMS (0.38) | TRPV1TYMSPSDCNR1PDE2A | |
| SCHEMBL13746667 | 0.70 | PDE2A (0.37) | TYMSPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100403-A1 | SUBSTITUTED ARYL PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |