Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 5/20 | 0.65 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020963 | 1.00 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL9935619 | 0.85 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL13977536 | 0.83 | PRCP (0.67) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL16308969 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL798381 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL8719925 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL1717271 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL4049149 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL10434781 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL16455043 | 0.81 | PRCP (0.68) | PRCPSLC22A1OPRM1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |