Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 5/20 | 0.65 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977536 | 0.83 | PRCP (0.67) | PRCPSLC22A1OPRM1GAASMN1; SMN2 | |
| SCHEMBL16455043 | 0.81 | PRCP (0.68) | PRCPSLC22A1OPRM1GAASMN1; SMN2 | |
| SCHEMBL16308969 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAASMN1; SMN2 | |
| SCHEMBL4049149 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAASMN1; SMN2 | |
| SCHEMBL8719925 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAASMN1; SMN2 | |
| SCHEMBL1717271 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAASMN1; SMN2 | |
| SCHEMBL10434781 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAASMN1; SMN2 | |
| SCHEMBL4020963 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAASMN1; SMN2 | |
| SCHEMBL4020702 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAASMN1; SMN2 | |
| SCHEMBL9935619 | 0.81 | PRCP (0.65) | PRCPSLC22A1OPRM1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072493-A | Novel synthesis method of 1-fluoromethyl-tetrahydroisoquinoline derivative | 中山大学 | 2021-07-06 | — | — | CN | claimed |
| CN-113072493-A | Novel synthesis method of 1-fluoromethyl-tetrahydroisoquinoline derivative | 中山大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-113072493-A | Novel synthesis method of 1-fluoromethyl-tetrahydroisoquinoline derivative | 中山大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-113072493-A | Novel synthesis method of 1-fluoromethyl-tetrahydroisoquinoline derivative | 中山大学 | 2021-07-06 | — | — | CN | disclosed |
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | disclosed |
| US-5686458-A | Quinazoline deriviates for treating peptic ulcer | YUHAN CORPORATION (KR) | 1997-11-11 | — | — | US | disclosed |
| EP-0677049-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014795-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION (KR) | 1994-07-07 | — | — | WO | disclosed |