SCHEMBL4021032

SCHEMBL4021032

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4CC(N5CCCCC5)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.67
CYP2C19 P33261 1/20 0.67
INPP5D Q92835 1/20 0.66
CDC25A P30304 4/20 0.59
POLA1 P09884 1/20 0.58
OSBP P22059 1/20 0.56
OSBP2 Q969R2 1/20 0.56
ST6GAL1 P15907 2/20 0.54
CASP7 P55210 3/20 0.52
SRD5A1 P18405 3/20 0.52
SRD5A2 P31213 3/20 0.52
TP53 P04637 2/20 0.52
MAPK1 P28482 2/20 0.52
HSD17B10 Q99714 2/20 0.52
GPBAR1 Q8TDU6 2/20 0.52
BLM P54132 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
HIF1A Q16665 2/20 0.52
MDM4 O15151 1/20 0.52
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13769841 1.00 CYP2D6 (0.67) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL4021026 1.00 CYP2D6 (0.67) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL4017496 0.90 CYP2D6 (0.65) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL4017489 0.90 CYP2D6 (0.65) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL13769849 0.90 CYP2D6 (0.65) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL11459235 0.88 CYP2D6 (0.67) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL11468426 0.88 CYP2D6 (0.67) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL11470540 0.88 CYP2D6 (0.67) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL11459234 0.88 CYP2D6 (0.67) CYP2D6CYP2C19INPP5DCDC25APOLA1
Epicoprosterol SCHEMBL25267973 0.83 OSBP (0.78) CYP2D6CYP2C19INPP5DCDC25APOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009090063-A1 STEROID SAPOGENIN, ANDROSTANE AND TRITERPENOID SAPOGENIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF INFECTIOUS DISEASES JADO TECHNOLOGIES GMBH (DE) 2009-07-23 WO disclosed