Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.49 |
| ▸ | AURKA | O14965 | 5/20 | 0.49 |
| ▸ | MET | P08581 | 5/20 | 0.49 |
| ▸ | TEK | Q02763 | 5/20 | 0.49 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 3/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | FGR | P09769 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | GPR6 | P46095 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021705 | 0.93 | PAK1 (0.50) | PAK1KDM4EMEN1KMT2AP2RX7 | |
| SCHEMBL4583078 | 0.93 | KDR (0.56) | KDRAURKAMETTEKPAK1 | |
| SCHEMBL4021559 | 0.88 | KDR (0.51) | KDRAURKAMETTEKPAK1 | |
| SCHEMBL4020031 | 0.85 | PAK1 (0.49) | KDRAURKAMETTEKPAK1 | |
| SCHEMBL4016348 | 0.83 | MEN1 (0.49) | PAK1KDM4EMEN1KMT2AP2RX7 | |
| SCHEMBL4018523 | 0.82 | ALDH1A1 (0.59) | PAK1KDM4EMEN1KMT2AP2RX7 | |
| SCHEMBL4024025 | 0.81 | PAK1 (0.63) | PAK1MEN1KMT2AP2RX7GPR6 | |
| SCHEMBL4016414 | 0.81 | PAK1 (0.63) | KDRAURKAMETTEKPAK1 | |
| SCHEMBL4024415 | 0.80 | PAK1 (0.52) | PAK1KDM4EMEN1KMT2AP2RX7 | |
| SCHEMBL4023212 | 0.80 | PAK1 (0.52) | PAK1KDM4EMEN1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |