Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022205 | 1.00 | CYP11B1 (0.35) | CYP11B1CYP11B2KCNN4KCNA3HDAC3 | |
| SCHEMBL4023393 | 1.00 | CYP11B1 (0.35) | CYP11B1CYP11B2KCNN4KCNA3HDAC3 | |
| SCHEMBL13389615 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2KCNN4KCNA3KMT2A | |
| SCHEMBL8921475 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2KCNN4KCNA3KMT2A | |
| SCHEMBL1757058 | 0.77 | HCAR2 (0.40) | CYP11B1CYP11B2HDAC3HDAC4HDAC1 | |
| SCHEMBL1757057 | 0.77 | HCAR2 (0.40) | CYP11B1CYP11B2HDAC3HDAC4HDAC1 | |
| SCHEMBL4022590 | 0.76 | CYP11B1 (0.40) | CYP11B1CYP11B2KCNN4KCNA3KMT2A | |
| SCHEMBL584685 | 0.76 | CYP11B1 (0.40) | CYP11B1CYP11B2KCNN4KCNA3KMT2A | |
| SCHEMBL7438606 | 0.71 | MLYCD (0.33) | CYP11B1CYP11B2HDAC3HDAC4HDAC1 | |
| SCHEMBL1757021 | 0.71 | NPC1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |