Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.57 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766549 | 0.85 | TK1 (0.62) | TK1POLB | |
| SCHEMBL8581389 | 0.82 | TK1 (0.59) | TK1POLB | |
| SCHEMBL5583976 | 0.80 | TK1 (0.61) | TK1 | |
| SCHEMBL25752530 | 0.80 | TK1 (0.70) | TK1POLB | |
| SCHEMBL5692576 | 0.80 | TK1 (0.57) | TK1 | |
| SCHEMBL888186 | 0.80 | TK1 (0.44) | TK1TOP2A | |
| SCHEMBL6379327 | 0.79 | TK1 (0.67) | TK1 | |
| SCHEMBL8999362 | 0.78 | TK1 (0.57) | TK1 | |
| SCHEMBL30995894 | 0.77 | TK1 (0.62) | TK1 | |
| SCHEMBL8585445 | 0.77 | TK1 (0.56) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879906-A4 | REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF | ADVANCED GENETIC ANALYSIS CORP (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1879906-A2 | REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF | AB Advanced Genetic Analysis Corporation (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006074351-A2 | REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF | AGENCOURT PERSONAL GENOMICS (US) | 2006-07-13 | — | — | WO | disclosed |