Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4202282 | 1.00 | CCR5 (0.81) | CCR5 | |
| SCHEMBL3940658 | 0.89 | CCR5 (1.00) | CCR5 | |
| SCHEMBL3943357 | 0.88 | CCR5 (1.00) | CCR5 | |
| SCHEMBL4093534 | 0.88 | CCR5 (1.00) | CCR5 | |
| SCHEMBL3935674 | 0.88 | CCR5 (1.00) | CCR5 | |
| SCHEMBL4204024 | 0.87 | CCR5 (0.82) | CCR5 | |
| SCHEMBL4206070 | 0.86 | CCR5 (1.00) | CCR5 | |
| SCHEMBL4018881 | 0.83 | CCR5 (0.55) | CCR5 | |
| SCHEMBL4198003 | 0.83 | CCR5 (0.84) | CCR5 | |
| SCHEMBL3934835 | 0.81 | CCR5 (0.72) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009013171-A2 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-01-29 | — | — | WO | claimed |