Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR1F | P30939 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617642 | 0.95 | HTR6 (0.54) | HTR6POLBL3MBTL1HTR1ADRD2 | |
| SCHEMBL3620151 | 0.94 | HTR6 (0.55) | HTR6POLBL3MBTL1HTR1ADRD2 | |
| SCHEMBL1992717 | 0.84 | HTR6 (0.49) | HTR6POLBL3MBTL1HTR1ADRD2 | |
| SCHEMBL3623694 | 0.83 | HTR6 (0.48) | HTR6POLBL3MBTL1HTR1ADRD2 | |
| SCHEMBL3619807 | 0.82 | HTR6 (0.62) | HTR6POLBL3MBTL1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL3623637 | 0.81 | HTR6 (0.60) | HTR6POLBL3MBTL1HTR1ADRD2 | |
| SCHEMBL3620380 | 0.81 | HTR6 (0.49) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3622018 | 0.78 | HTR6 (0.58) | HTR6HTR1ADRD2HTR1DHTR1B | |
| Trifluoroacetic Acid SCHEMBL3619186 | 0.76 | HTR6 (0.44) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3622889 | 0.74 | HTR6 (0.57) | HTR6POLBL3MBTL1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046741-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (publ) (SE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008003703-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2008-01-10 | — | — | WO | disclosed |