Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 7/20 | 0.57 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581785 | 0.95 | PAK1 (0.63) | PAK1KITP2RX7RAB9ADRD4 | |
| SCHEMBL4016188 | 0.94 | PAK1 (0.59) | PAK1KITP2RX7RAB9ADRD4 | |
| SCHEMBL4021914 | 0.88 | PAK1 (0.63) | PAK1KITP2RX7RAB9ADRD4 | |
| SCHEMBL4018133 | 0.87 | PAK1 (0.72) | PAK1P2RX7DRD4RPS6KB1MEN1 | |
| SCHEMBL4018426 | 0.85 | PAK1 (0.59) | PAK1KITP2RX7RAB9AMEN1 | |
| SCHEMBL4581607 | 0.85 | PAK1 (0.65) | PAK1KITP2RX7DRD4MEN1 | |
| SCHEMBL4016261 | 0.85 | DRD2 (0.47) | PAK1P2RX7DRD4RPS6KB1MEN1 | |
| SCHEMBL4025750 | 0.84 | PAK1 (0.66) | PAK1P2RX7MEN1KMT2ACNR1 | |
| SCHEMBL4024568 | 0.84 | PAK1 (0.68) | PAK1P2RX7MEN1KMT2ACNR1 | |
| SCHEMBL4019827 | 0.83 | PAK1 (0.56) | PAK1KITP2RX7DRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |