Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 18/20 | 0.70 |
| ▸ | RARB | P10826 | 16/20 | 0.70 |
| ▸ | RARA | P10276 | 15/20 | 0.70 |
| ▸ | RXRA | P19793 | 14/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.70 |
| ▸ | GMNN | O75496 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | THPO | P40225 | 1/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022980 | 1.00 | RARG (0.70) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL11554361 | 0.90 | RARG (0.66) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL11554363 | 0.90 | RARG (0.66) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL6428636 | 0.86 | RARG (0.54) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL11211048 | 0.83 | RARG (0.57) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL11211053 | 0.83 | RARG (0.57) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL2307487 | 0.83 | RARB (1.00) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL345071 | 0.83 | RARB (1.00) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL177444 | 0.83 | RARB (1.00) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL29836848 | 0.83 | RARB (1.00) | RARGRARBRARARXRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501487-B1 | Retinoid receptor compositions and methods | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2009-03-10 | — | — | US | disclosed |
| EP-0514488-B1 | RETINOID RECEPTOR COMPOSITIONS AND METHODS | SALK INST FOR BIOLOGICAL STUDI (US) | 2000-09-13 | — | — | EP | disclosed |
| EP-0999271-A2 | Retinoid receptor compositions and methods | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2000-05-10 | — | — | EP | disclosed |
| WO-1995033745-A9 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | — | 1996-01-18 | — | — | WO | disclosed |
| EP-0514488-A4 | RETINOID RECEPTOR COMPOSITIONS AND METHODS | — | 1993-02-17 | — | — | EP | disclosed |
| EP-0514488-A1 | RETINOID RECEPTOR COMPOSITIONS AND METHODS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991012258-A1 | RETINOID RECEPTOR COMPOSITIONS AND METHODS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1991-08-22 | — | — | WO | disclosed |