Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HMGCR | P04035 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14126011 | 0.88 | MTNR1A (0.54) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL3833716 | 0.84 | GAA (0.57) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL30053264 | 0.83 | HSD17B10 (0.51) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL3409461 | 0.83 | HSD17B10 (0.51) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL28603326 | 0.82 | HMGCR (0.61) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL1498704 | 0.82 | HMGCR (0.52) | TSHRHMGCRMTNR1AMTNR1BMAPK1 | |
| SCHEMBL22774455 | 0.82 | HSD17B10 (0.47) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL29431303 | 0.82 | HSD17B10 (0.47) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL5373257 | 0.82 | HSD17B10 (0.47) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL15760015 | 0.81 | HSD17B10 (0.57) | GAAALDH1A1TSHRNFKB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117310025-A | Method for screening key metabolites and pathways of ketosis based on double-platform metabolome | 宁夏大学 | 2023-12-29 | — | — | CN | disclosed |
| WO-2009097144-A1 | MOLECULAR PROBES FOR PET-IMAGING OF DOPAMINE NEUROTRANSMISSION AND NEUROENDOCRINE PROCESSES IN VIVO | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-08-06 | — | — | WO | disclosed |