Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023601 | 1.00 | TK1 (1.00) | TK1LMNATSHRALBPKM | |
| SCHEMBL4023603 | 1.00 | TK1 (1.00) | TK1LMNATSHRALBPKM | |
| SCHEMBL11959639 | 0.94 | TK1 (0.89) | TK1LMNATSHRALBPKM | |
| SCHEMBL11959617 | 0.91 | TK1 (0.83) | TK1LMNATSHRALBPKM | |
| SCHEMBL13464002 | 0.88 | TK1 (1.00) | TK1LMNATSHRALBPKM | |
| SCHEMBL3618060 | 0.88 | TK1 (1.00) | TK1LMNATSHRALBPKM | |
| SCHEMBL3616937 | 0.88 | TK1 (1.00) | TK1LMNATSHRALBPKM | |
| SCHEMBL3618062 | 0.88 | TK1 (1.00) | TK1LMNATSHRALBPKM | |
| SCHEMBL3616931 | 0.88 | TK1 (1.00) | TK1LMNATSHRALBPKM | |
| SCHEMBL13464001 | 0.88 | TK1 (1.00) | TK1LMNATSHRALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879906-A4 | REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF | ADVANCED GENETIC ANALYSIS CORP (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1879906-A2 | REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF | AB Advanced Genetic Analysis Corporation (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006074351-A2 | REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF | AGENCOURT PERSONAL GENOMICS (US) | 2006-07-13 | — | — | WO | disclosed |