Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023658 | 1.00 | MGLL (0.38) | MGLLCA12CA1CA2CA6 | |
| SCHEMBL4025189 | 0.91 | MGLL (0.38) | MGLLKMT2AMEN1SLC2A1SLC2A4 | |
| SCHEMBL4025192 | 0.91 | MGLL (0.38) | MGLLKMT2AMEN1SLC2A1SLC2A4 | |
| SCHEMBL4019096 | 0.87 | MGLL (0.35) | MGLLKMT2AMEN1SLC2A1SLC2A4 | |
| SCHEMBL4019088 | 0.87 | MGLL (0.35) | MGLLKMT2AMEN1SLC2A1SLC2A4 | |
| SCHEMBL4749182 | 0.86 | MGLL (0.39) | MGLLKMT2AMEN1 | |
| SCHEMBL4805388 | 0.86 | MGLL (0.39) | MGLLKMT2AMEN1 | |
| SCHEMBL4751652 | 0.86 | MGLL (0.39) | MGLLKMT2AMEN1 | |
| SCHEMBL4805380 | 0.86 | MGLL (0.39) | MGLLKMT2AMEN1 | |
| SCHEMBL4751581 | 0.86 | KMT2A (0.46) | MGLLKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |