Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26803733 | 0.81 | DAO (0.44) | DAOHDAC1FFAR1HTR2AHTR2C | |
| SCHEMBL2786582 | 0.81 | CYP11B1 (0.48) | DAOMAPK1FFAR1HTR2AHTR2C | |
| SCHEMBL29009736 | 0.80 | FFAR1 (0.55) | DAOFFAR1HTR2AHTR2CKCNH2 | |
| SCHEMBL29404687 | 0.80 | FFAR1 (0.55) | DAOFFAR1HTR2AHTR2CKCNH2 | |
| SCHEMBL27365024 | 0.75 | RAB9A (0.55) | DAOFFAR1HPGD | |
| SCHEMBL3299826 | 0.75 | CYP4F2 (0.46) | DAOPOLBHPGD | |
| SCHEMBL4749498 | 0.74 | ACACB (0.54) | DAOHPGDMTNR1AMTNR1B | |
| SCHEMBL12228279 | 0.74 | HPGD (0.56) | FFAR1P2RX7HPGD | |
| SCHEMBL3937280 | 0.73 | FFAR1 (0.45) | DAOHDAC1HDAC6MAPK1FFAR1 | |
| SCHEMBL12851363 | 0.73 | HRH3 (0.56) | MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095712-A2 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-06 | — | — | WO | disclosed |