Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | F7 | P08709 | 3/20 | 0.62 |
| ▸ | F3 | P13726 | 3/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PPARD | Q03181 | 2/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29706306 | 1.00 | ALDH1A1 (0.62) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL4023965 | 1.00 | ALDH1A1 (0.62) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL1416855 | 0.95 | EPHX2 (0.54) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL4021981 | 0.95 | EPHX2 (0.54) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL4021951 | 0.93 | EPHX2 (0.53) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL4021960 | 0.93 | EPHX2 (0.53) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL16694967 | 0.90 | KDM4E (0.64) | ALDH1A1F7F3CYP19A1PTGS1 | |
| SCHEMBL4017990 | 0.90 | KDM4E (0.64) | ALDH1A1F7F3CYP19A1PTGS1 | |
| SCHEMBL30381949 | 0.90 | KDM4E (0.64) | ALDH1A1F7F3CYP19A1PTGS1 | |
| SCHEMBL4017897 | 0.90 | KDM4E (0.64) | ALDH1A1F7F3CYP19A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476756-B2 | Alkyl-, alkenyl- and alkynylcarbamate derivatives, their preparation and their application in therapeutics | SANOFI-AVENTIS (FR) | 2009-01-13 | — | — | US | disclosed |
| US-20080103197-A1 | ALKYL-, ALKENYL- AND ALKYNYLCARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103197-A1 | ALKYL-, ALKENYL- AND ALKYNYLCARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | ALK, ALKBH3, IDH1 | ALDH1A1 17/4885F7 3440/4885F3 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.