Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021050 | 0.88 | LMNA (0.45) | LMNAFFAR1MAPTPPARDBLM | |
| SCHEMBL15775240 | 0.87 | LMNA (0.48) | LMNAFDPSGPR84SPHK1FFAR1 | |
| SCHEMBL10457247 | 0.84 | LMNA (0.54) | LMNAFDPSGPR84SPHK1FFAR1 | |
| SCHEMBL12477841 | 0.80 | LMNA (0.50) | LMNAFDPSGPR84SPHK1FFAR1 | |
| SCHEMBL5176712 | 0.80 | LMNA (0.50) | LMNAFDPSGPR84SPHK1FFAR1 | |
| SCHEMBL29286434 | 0.80 | LMNA (0.50) | LMNAFDPSGPR84SPHK1FFAR1 | |
| SCHEMBL25907082 | 0.78 | LMNA (0.52) | LMNAFDPSGPR84SPHK1FFAR1 | |
| SCHEMBL28493573 | 0.77 | LCK (0.45) | LMNAFDPSGPR84SPHK1FFAR1 | |
| SCHEMBL24920054 | 0.76 | LMNA (0.50) | LMNAFDPSGPR84MAPTDNM1 | |
| SCHEMBL20809768 | 0.76 | LMNA (0.50) | LMNAFDPSGPR84MAPTDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059257-A2 | USE OF GLYCOLIPIDS AS ADJUVANTS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008028667-A2 | USE OF GLYCOLIPIDS AS ADJUVANTS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2008-03-13 | — | — | WO | disclosed |