Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3625913 | 0.86 | HTR6 (0.52) | HTR6CYP3A4CYP2D6RAB9AHTR1A | |
| Trifluoroacetic Acid SCHEMBL3622318 | 0.86 | HTR6 (0.52) | HTR6CYP3A4CYP2D6RAB9AHTR1A | |
| Trifluoroacetic Acid SCHEMBL4024854 | 0.85 | HTR6 (0.64) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL3623167 | 0.85 | HTR6 (0.69) | HTR6CYP3A4CYP2D6RAB9A | |
| Trifluoroacetic Acid SCHEMBL4024567 | 0.85 | HTR6 (0.71) | HTR6CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL4021360 | 0.84 | HTR6 (0.57) | HTR6CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL4021249 | 0.83 | HTR6 (0.61) | HTR6CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL4019247 | 0.83 | HTR6 (0.60) | HTR6CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL4021316 | 0.83 | HTR6 (0.60) | HTR6CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL4022973 | 0.82 | HTR6 (0.67) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046741-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (publ) (SE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008003703-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2008-01-10 | — | — | WO | disclosed |