Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026430 | 0.92 | ADORA1 (0.46) | ADORA1ADORA2AALOX15ALDH1A1KDM4E | |
| SCHEMBL4022211 | 0.79 | ADORA1 (0.58) | ADORA1ADORA2ATSHRALOX15ALDH1A1 | |
| SCHEMBL4023617 | 0.79 | ADORA1 (0.63) | ADORA1ADORA2ATSHRALOX15ALDH1A1 | |
| SCHEMBL4024199 | 0.76 | ADORA1 (0.55) | ADORA1ADORA2ATSHRALOX15ALDH1A1 | |
| SCHEMBL4025782 | 0.76 | ADORA1 (0.59) | ADORA1ADORA2ATSHRALOX15ALDH1A1 | |
| SCHEMBL13848826 | 0.75 | ADORA1 (0.56) | ADORA1ADORA2ATSHRALOX15ALDH1A1 | |
| SCHEMBL5951299 | 0.75 | ADORA1 (0.46) | ADORA1ADORA2AALOX15ALDH1A1KDM4E | |
| SCHEMBL4191367 | 0.73 | ADORA1 (0.51) | ADORA1ADORA2ATSHRALOX15ALDH1A1 | |
| SCHEMBL6583277 | 0.73 | ADORA1 (0.61) | ADORA1ADORA2ATSHRALOX15ALDH1A1 | |
| SCHEMBL4028154 | 0.73 | ADORA1 (0.56) | ADORA1ADORA2ATSHRALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377570-B1 | SUBSTITUTED 2-CARBA-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THE USE OF THE SAME AS SELECTIVE LIGANDS OF THE ADENOSINE RECEPTOR | BAYER HEALTHCARE AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-7129255-B2 | Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and the use of the same as selective ligands of the adenosine receptor | BAYER AKTIENGESELLSCHAFT (DE) | 2006-10-31 | — | — | US | disclosed |
| US-20040110946-A1 | Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and the use of the same as selective ligands of the adenosine receptor | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
| EP-1377570-A1 | SUBSTITUTED 2-CARBA-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THE USE OF THE SAME AS SELECTIVE LIGANDS OF THE ADENOSINE RECEPTOR | Bayer HealthCare AG (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002079196-A1 | SUBSTITUTED 2-CARBA-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THE USE OF THE SAME AS SELECTIVE LIGANDS OF THE ADENOSINE RECEPTOR | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110946-A1 | Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and the use of the same as selective ligands of the adenosine receptor | ADORA3, ADORA1, ADORA2A | ADORA1 2/4885ADORA2A 3/4885TSHR 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.