Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | SCARB1 | Q8WTV0 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023805 | 0.91 | SCARB1 (0.61) | CNR2SCARB1BRD4NPC1HSD17B10 | |
| SCHEMBL4032892 | 0.87 | CNR2 (0.50) | CNR2SCARB1HSD17B10ACLYDYRK1A | |
| SCHEMBL30981928 | 0.81 | HSD17B10 (0.46) | CNR2SCARB1HSD17B10KDM4EPTGDR2 | |
| SCHEMBL30981996 | 0.79 | KRAS (0.46) | CNR2SCARB1HSD17B10KDM4EPTGDR2 | |
| SCHEMBL23166612 | 0.79 | CNR2 (0.57) | CNR2BRD4DYRK1A | |
| SCHEMBL29708174 | 0.79 | CNR2 (0.57) | CNR2BRD4DYRK1A | |
| SCHEMBL4560319 | 0.77 | SCARB1 (0.61) | SCARB1NPC1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL4023636 | 0.77 | SCARB1 (0.72) | SCARB1NPC1HSD17B10FABP4KDM4E | |
| SCHEMBL10732414 | 0.77 | CHRM2 (0.64) | CNR2SCARB1NPC1HSD17B10FABP4 | |
| SCHEMBL30981942 | 0.76 | PTGDR2 (0.44) | CNR2HSD17B10PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |