Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 4/20 | 0.44 |
| ▸ | SCARB1 | Q8WTV0 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30981928 | 0.94 | HSD17B10 (0.46) | CNR2KRASSCARB1HSD17B10HDAC1 | |
| SCHEMBL30981996 | 0.92 | KRAS (0.46) | CNR2KRASSCARB1HSD17B10CAMK2D | |
| SCHEMBL4024465 | 0.87 | CNR2 (0.56) | CNR2SCARB1HSD17B10DYRK1AACLY | |
| SCHEMBL4023805 | 0.87 | SCARB1 (0.61) | CNR2SCARB1HSD17B10HDAC1HDAC6 | |
| SCHEMBL30981976 | 0.86 | MTNR1A (0.44) | CNR2KRASHSD17B10CAMK2DHDAC1 | |
| SCHEMBL15798202 | 0.81 | CNR2 (0.67) | CNR2CAMK2DHDAC1HDAC6DYRK1A | |
| SCHEMBL30981883 | 0.79 | KRAS (0.60) | CNR2KRASHDAC1HDAC6 | |
| SCHEMBL15798230 | 0.79 | DYRK1A (0.56) | CNR2CAMK2DDYRK1A | |
| SCHEMBL30981942 | 0.77 | PTGDR2 (0.44) | CNR2HSD17B10 | |
| SCHEMBL30981901 | 0.77 | MTNR1A (0.39) | CNR2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |