Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 11/20 | 0.38 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022127 | 0.92 | KDM2B (0.39) | DRD4DRD2KDM2BMCHR1CYP2C9 | |
| SCHEMBL4023627 | 0.92 | KDM2B (0.39) | DRD4DRD2KDM2BMCHR1CYP2C9 | |
| SCHEMBL4023629 | 0.92 | KDM2B (0.39) | DRD4DRD2KDM2BMCHR1CYP2C9 | |
| SCHEMBL13721312 | 0.92 | KDM2B (0.39) | DRD4DRD2KDM2BMCHR1CYP2C9 | |
| SCHEMBL4749342 | 0.91 | KDM2B (0.40) | DRD4DRD2ALDH1A1LMNAKDM2B | |
| SCHEMBL4751954 | 0.87 | DRD4 (0.44) | DRD4DRD2KDM2BDRD3KMT2A | |
| SCHEMBL4025349 | 0.86 | DRD4 (0.43) | DRD4DRD2KDM2BDRD3KMT2A | |
| SCHEMBL4020026 | 0.85 | KDM2B (0.42) | DRD2ALDH1A1KDM2BMCHR1CYP2C9 | |
| SCHEMBL4019477 | 0.84 | DRD4 (0.41) | DRD4DRD2KDM2BMCHR1CYP2C9 | |
| SCHEMBL4021684 | 0.83 | KDM2B (0.38) | DRD4DRD2KDM2BMCHR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |