Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 6/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020026 | 0.94 | KDM2B (0.42) | KDM2BALDH1A1MCHR1DRD2DRD3 | |
| SCHEMBL4026436 | 0.92 | KDM2B (0.42) | KDM2BALDH1A1LMNAMCHR1DRD2 | |
| SCHEMBL4024586 | 0.91 | DRD4 (0.38) | KDM2BALDH1A1LMNADRD4MCHR1 | |
| SCHEMBL4021139 | 0.88 | KDM2B (0.43) | KDM2BMCHR1DRD2DRD3MC4R | |
| SCHEMBL4022270 | 0.84 | KDM2B (0.39) | KDM2BALDH1A1DRD4DRD2KMT2A | |
| SCHEMBL4024597 | 0.84 | KDM2B (0.45) | KDM2BALDH1A1LMNADRD2DRD3 | |
| SCHEMBL4021398 | 0.84 | KDM2B (0.45) | KDM2BALDH1A1LMNADRD2DRD3 | |
| SCHEMBL4749206 | 0.83 | KDM2B (0.42) | KDM2BALDH1A1LMNADRD2DRD3 | |
| SCHEMBL4029178 | 0.82 | KDM2B (0.43) | KDM2BDRD4DRD2KMT2ANPSR1 | |
| SCHEMBL4022832 | 0.82 | KDM2B (0.43) | KDM2BDRD4DRD2KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |