SCHEMBL4024762

SCHEMBL4024762

O=S(=O)(O)c1ncccn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
COMT P21964 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
KDM4E B2RXH2 4/20 0.39
ALOX12 P18054 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP1A2 P05177 2/20 0.37
HIF1A Q16665 2/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
BLM P54132 2/20 0.35
POLB P06746 1/20 0.35
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27678895 0.97 COMT (0.38) COMTNAPRTKDM4EALOX12SMN1; SMN2
Fluoride SCHEMBL27616949 0.97 COMT (0.38) COMTNAPRTKDM4EALOX12SMN1; SMN2
Hydrochloric Acid SCHEMBL27466194 0.97 COMT (0.38) COMTNAPRTKDM4EALOX12SMN1; SMN2
Water SCHEMBL27735781 0.95 COMT (0.37) COMTNAPRTKDM4EALOX12SMN1; SMN2
Pyridine SCHEMBL27582659 0.88 NAPRT (0.42) COMTNAPRTKDM4EALOX12SMN1; SMN2
Pyridine SCHEMBL27722277 0.86 NAPRT (0.41) COMTNAPRTKDM4EALOX12SMN1; SMN2
Pyridine SCHEMBL27750161 0.82 NAPRT (0.38) COMTNAPRTKDM4EALOX12SMN1; SMN2
SCHEMBL19741153 0.79 COMT (0.30) COMT
Pyridine SCHEMBL27569690 0.78 NAPRT (0.35) NAPRTKDM4ETSHRTDP1
SCHEMBL5593062 0.75 TXNRD1 (0.37) KDM4EALOX12LMNATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118354672-A Fungicidal compositions 先正达农作物保护股份公司 2024-07-16 CN claimed
CN-114669280-B Purifying filler for sulfonamide residue and pretreatment method 深圳市易瑞生物技术股份有限公司 2023-10-27 CN claimed
CN-116200393-A Mixed broad-spectrum nucleic acid aptamer for simultaneously detecting 9 sulfonamide drugs 福州大学 2023-06-02 CN claimed
CN-114181157-A Monofluorosulfonyl olefin, and preparation method and application thereof 中国科学院兰州化学物理研究所 2022-03-15 CN claimed
CN-105596356-A Compositions and methods for combination antiviral therapy GILEAD SCIENCES INC 2016-05-25 CN claimed
CN-101027062-A Phosphonate analogs of HIV inhibitor compounds GILEAD SCIENCES INC (US) 2007-08-29 CN claimed
CN-1982325-A Heteroconfigurational polynucleotides and methods of use APPLERA CORP APPLIED BIOSYSTEM (US) 2007-06-20 CN claimed
CN-1780631-A anticancer phosphonate analogs GILEAD SCIENCES INC (US) 2006-05-31 CN claimed
CN-1780643-A Antiviral phosphonate analogs GILEAD SCIENCES INC (US) 2006-05-31 CN claimed
CN-1738628-A Compositions and methods for combination antiviral therapy GILEAD SCIENCES INC (US) 2006-02-22 CN claimed
CN-1628124-A Heteroconfigurational polynucleotides and methods of use thereof APPLERA CORP (US) 2005-06-15 CN claimed
CN-1443174-A Fungicidal 5-phenyl substituted 2- (cyanamido) pyrimidines BASF AG (DE) 2003-09-17 CN claimed
US-5977169-A FOR TREATMENT OF A PERSON WITH AIDS OR AIDS RELATED DISEASES PHARMACIA & UPJOHN COMPANY 1999-11-02 US claimed
EP-0720607-A1 SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES PHARMACIA & UPJOHN COMPANY (US) 1996-07-10 EP claimed
WO-1995007901-A1 SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES THE UPJOHN COMPANY (US) 1995-03-23 WO claimed
WO-2025103220-A1 PYRIDYL ALKOXY PYRIMIDINE COMPOUND AND USE THEREOF 青岛清原化合物有限公司 2025-05-22 WO disclosed
CN-119855815-A KRAS mutant protein inhibitor, and preparation method and application thereof 甘李药业股份有限公司 2025-04-18 CN disclosed
EP-0720607-A1 SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES PHARMACIA & UPJOHN COMPANY (US) 1996-07-10 EP disclosed
WO-1995007901-A1 SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES THE UPJOHN COMPANY (US) 1995-03-23 WO disclosed
CN-1087089-A The treatment nucleosides WELLCOME FOUND (GB) 1994-05-25 CN disclosed