Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | STAT5B | P51692 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662150 | 0.81 | BRD4 (0.32) | BRD4 | |
| SCHEMBL2954642 | 0.79 | CYP11B1 (0.40) | BRD4 | |
| SCHEMBL2955159 | 0.73 | POLB (0.32) | BRD4 | |
| SCHEMBL661400 | 0.73 | TLR8 (0.41) | BRD4 | |
| SCHEMBL4025360 | 0.73 | HCAR2 (0.32) | BRD4 | |
| SCHEMBL662267 | 0.72 | CYP2C9 (0.34) | ALDH1A1BRD4 | |
| SCHEMBL660548 | 0.72 | ALDH1A1 (0.41) | ALDH1A1BRD4 | |
| SCHEMBL20591073 | 0.71 | ALDH1A1 (0.40) | ALDH1A1STAT5B | |
| SCHEMBL663057 | 0.71 | BRD4 (0.35) | ALDH1A1BRD4 | |
| SCHEMBL12724434 | 0.71 | ALDH1A1 (0.41) | ALDH1A1BRD4STAT5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050736-A1 | Imidazole derivatives, processes for preparing them and their uses | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | disclosed |
| EP-1706376-B1 | IMIDAZOLE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA SA (BE) | 2009-03-04 | — | — | EP | disclosed |