Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171971 | 0.87 | THRA (0.47) | PLA2G2DPPARDPPARGPPARACNR2 | |
| SCHEMBL2955178 | 0.87 | THRA (0.47) | PLA2G2DPPARDPPARGPPARACNR2 | |
| SCHEMBL4018047 | 0.86 | THRA (0.45) | PLA2G2DPPARDPPARGPPARACNR2 | |
| SCHEMBL3180727 | 0.83 | THRA (0.43) | PLA2G2DPPARDPPARGPPARACNR2 | |
| SCHEMBL2945532 | 0.80 | THRA (0.44) | PLA2G2DPPARDPPARGPPARACNR2 | |
| SCHEMBL2945531 | 0.80 | THRA (0.44) | PLA2G2DPPARDPPARGPPARACNR2 | |
| SCHEMBL2957021 | 0.79 | DDR1 (0.35) | CNR2 | |
| SCHEMBL3944697 | 0.79 | THRA (0.45) | PLA2G2DPPARDPPARGPPARACNR2 | |
| SCHEMBL2946699 | 0.78 | S1PR1 (0.37) | PPARDPPARGPPARACNR2THRA | |
| SCHEMBL2952131 | 0.77 | PDE4A (0.37) | PPARDPPARGPPARACNR2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046746-A2 | CHEMICAL COMPOUNDS | Praecis Pharmaceuticals Incorporated (US) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008016692-A2 | CHEMICAL COMPOUNDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-02-07 | — | — | WO | disclosed |