SCHEMBL402517

SCHEMBL402517

Cc1ccc2c(c1)COCc1cc(C)ccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 3/20 0.42
PARP10 Q53GL7 1/20 0.41
PARP11 Q9NR21 1/20 0.41
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
PKM P14618 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 2/20 0.36
ELANE P08246 1/20 0.35
SRD5A1 P18405 1/20 0.35
ACHE P22303 1/20 0.34
LMNA P02545 1/20 0.34
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23981935 0.90 ELANE (0.42) METAP1PARP10PARP11KDM4EALDH1A1
SCHEMBL26767879 0.88 ESR1 (0.44) METAP1KDM4EALDH1A1MAPTGAA
SCHEMBL19835916 0.86 METAP1 (0.37) METAP1PARP10PARP11KDM4EALDH1A1
SCHEMBL8473057 0.86 METAP1 (0.44) METAP1PARP10PARP11KDM4EALDH1A1
SCHEMBL14985635 0.85 CYP2A6 (0.45) METAP1PARP10PARP11KDM4EALDH1A1
SCHEMBL26767717 0.84 TP53 (0.42) METAP1PARP10PARP11KDM4EALDH1A1
SCHEMBL3896106 0.83 IKBKB (0.41) METAP1PARP10PARP11KDM4EALDH1A1
SCHEMBL30743772 0.83 IKBKB (0.41) METAP1PARP10PARP11KDM4EALDH1A1
SCHEMBL14985662 0.81 KDM4E (0.42) METAP1PARP10PARP11KDM4EALDH1A1
SCHEMBL26767723 0.81 PRKCG (0.40) METAP1PARP10PARP11ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319410-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2022-05-03 US disclosed
US-20200331832-A1 EPOXY COMPOUND, COMPOSITION, CURED PRODUCT AND LAMINATE DIC CORPORATION (JP) 2020-10-22 US disclosed
US-10731004-B2 Polyimide precursor composition and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2020-08-04 US disclosed
US-20180194899-A1 PRECURSOR FOR POLYIMIDE AND USE THEREOF ETERNAL MATERIALS CO., LTD. (TW) 2018-07-12 US disclosed
US-20180148541-A1 POLYIMIDE PRECURSOR COMPOSITION AND USE THEREOF ETERNAL MATERIALS CO., LTD. (TW) 2018-05-31 US disclosed
US-9172052-B2 Phosphorescent OLED CDT OXFORD LIMITED (GB) 2015-10-27 US disclosed
US-20120065338-A1 PHOSPHORESCENT OLED CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-03-15 US disclosed
US-20090236972-A1 PHOSPHORESCENT OLED CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2009-09-24 US disclosed
US-20090066238-A1 Electroluminescent materials grafted with charge transport moieties having graded ionization potential or electrophilic property and their application in light-emitting diodes NATIONAL TSING HUA UNIVERSITY (TW) 2009-03-12 US disclosed
US-20090066238-A1 Electroluminescent materials grafted with charge transport moieties having graded ionization potential or electrophilic property and their application in light-emitting diodes NATIONAL TSING HUA UNIVERSITY (TW) 2009-03-12 US disclosed
US-7220819-B2 Electroluminescent conjugated polymers containing phosphorescent moieties and the application thereof in LED NATIONAL TSING HUA UNIVERSITY (TW) 2007-05-22 US disclosed
US-7220819-B2 Electroluminescent conjugated polymers containing phosphorescent moieties and the application thereof in LED NATIONAL TSING HUA UNIVERSITY (TW) 2007-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200331832-A1 EPOXY COMPOUND, COMPOSITION, CURED PRODUCT AND LAMINATE ARL1, DOT1L, RFT1 METAP1 3989/4885PARP10 380/4885PARP11 287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.