SCHEMBL4025281

SCHEMBL4025281

CCCCCCCCCCCCOCC(COC)OC=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.49
PRKD3 O94806 1/20 0.46
PRKCG P05129 1/20 0.46
PRKCB P05771 1/20 0.46
PRKCA P17252 1/20 0.46
PRKCH P24723 1/20 0.46
PRKCI P41743 1/20 0.46
PRKCE Q02156 1/20 0.46
PRKCQ Q04759 1/20 0.46
PRKCZ Q05513 1/20 0.46
PRKCD Q05655 1/20 0.46
PRKD1 Q15139 1/20 0.46
LPAR1 Q92633 9/20 0.45
LPAR3 Q9UBY5 9/20 0.45
LPAR5 Q9H1C0 4/20 0.45
LPAR2 Q9HBW0 4/20 0.45
LPAR6 P43657 3/20 0.45
LPAR4 Q99677 3/20 0.45
HTT P42858 2/20 0.43
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14843034 0.79 PRKD3 (0.68) USP2PRKD3PRKCGPRKCBPRKCA
SCHEMBL7032675 0.79 PRKD3 (0.68) USP2PRKD3PRKCGPRKCBPRKCA
SCHEMBL18519898 0.79 PRKD3 (0.68) USP2PRKD3PRKCGPRKCBPRKCA
SCHEMBL14842644 0.79 PRKD3 (0.68) USP2PRKD3PRKCGPRKCBPRKCA
SCHEMBL26225487 0.78 LMNA (0.60) PRKCAPRKCEPRKCQPRKCDLPAR1
SCHEMBL19829619 0.77 LPAR1 (0.62) USP2PRKD3PRKCGPRKCBPRKCA
SCHEMBL16303701 0.77 LPAR1 (0.62) USP2PRKD3PRKCGPRKCBPRKCA
SCHEMBL14877975 0.77 LPAR1 (0.62) USP2PRKD3PRKCGPRKCBPRKCA
SCHEMBL13659941 0.77 LPAR1 (0.62) USP2PRKD3PRKCGPRKCBPRKCA
SCHEMBL15158747 0.77 LPAR1 (0.62) USP2PRKD3PRKCGPRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2049630-A2 LUBRICANT COMPOSITION Ciba Holding Inc. (CH) 2009-04-22 EP disclosed
WO-2008015116-A2 LUBRICANT COMPOSITION CIBA HOLDING INC. (CH) 2008-02-07 WO disclosed