SCHEMBL4025817

SCHEMBL4025817

c1ccc(Oc2cccc(Oc3cccc(Oc4cccc(Oc5cccc(Oc6cccc(Oc7ccccc7)c6)c5)c4)c3)c2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.75
TSHR P16473 1/20 0.75
MAOB P27338 1/20 0.68
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
ALDH1A1 P00352 2/20 0.64
MITF O75030 1/20 0.64
GAA P10253 1/20 0.64
MAPT P10636 1/20 0.64
GFER P55789 1/20 0.64
NLRP1 Q9C000 1/20 0.64
NOD2 Q9HC29 1/20 0.64
AKR1C3 P42330 1/20 0.60
NR1H2 P55055 1/20 0.55
BAX Q07812 1/20 0.55
MAOA P21397 1/20 0.55
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
NLRP3 Q96P20 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22559 1.00 LTA4H (0.75) LTA4HTSHRMAOBMEN1KMT2A
SCHEMBL380685 1.00 LTA4H (0.75) LTA4HTSHRMAOBMEN1KMT2A
SCHEMBL30211827 1.00 LTA4H (0.75) LTA4HTSHRMAOBMEN1KMT2A
SCHEMBL1173869 1.00 LTA4H (0.75) LTA4HTSHRMAOBMEN1KMT2A
SCHEMBL30018242 1.00 LTA4H (0.75) LTA4HTSHRMAOBMEN1KMT2A
SCHEMBL1173711 1.00 LTA4H (0.75) LTA4HTSHRMAOBMEN1KMT2A
SCHEMBL3893288 0.97 LTA4H (0.71) LTA4HTSHRMAOBMEN1KMT2A
SCHEMBL436010 0.97 LTA4H (0.71) LTA4HTSHRMAOBMEN1KMT2A
SCHEMBL9216135 0.97 LTA4H (0.71) LTA4HTSHRMAOBMEN1KMT2A
SCHEMBL3888963 0.97 LTA4H (0.71) LTA4HTSHRMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7511113-B2 Oligomeric hydroxy arylether phthalonitiles and synthesis thereof THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2009-03-31 US disclosed
US-7452959-B2 Oligomeric hydroxy arylether phthalonitiles and synthesis thereof THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-11-18 US disclosed
EP-1507816-A4 OLIGOMERIC HYDROXY ARYLETHER PHTHALONITILES AND SYNTHESIS THEREOF US GOV SEC NAVY (US) 2006-05-31 EP disclosed
US-6891014-B2 Oligomeric hydroxy arylether phthalonitiles and synthesis thereof THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2005-05-10 US disclosed
EP-1507816-A1 OLIGOMERIC HYDROXY ARYLETHER PHTHALONITILES AND SYNTHESIS THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (US) 2005-02-23 EP disclosed
US-20040181029-A1 Oligomeric hydroxy arylether phthalonitiles and synthesis thereof UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY, THE 2004-09-16 US disclosed
US-20040181027-A1 Oligomeric hydroxy arylether phthalonitiles and synthesis thereof NAVY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2004-09-16 US disclosed
US-20040181028-A1 Oligomeric hydroxy arylether phthalonitiles and synthesis thereof NAVY, THE, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2004-09-16 US disclosed
US-6756470-B2 Oligomeric hydroxy arylether phthalonitiles and synthesis thereof THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2004-06-29 US disclosed
US-20030229198-A1 Oligomeric hydroxy arylether phthalonitiles and synthesis thereof NAVY, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF, THE 2003-12-11 US disclosed
WO-2003091312-A1 OLIGOMERIC HYDROXY ARYLETHER PHTHALONITILES AND SYNTHESIS THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRSENTED BY THE SECRETARY OF THE NAVY (US) 2003-11-06 WO disclosed
US-5464569-A In situ formation of alkali metal oxalates in polyphenylene ether basestock MONSANTO COMPANY (US) 1995-11-07 US disclosed
US-5439614-A Colloidal dispersion of aromatic ether and oxidation inhibiting amount of alkali metal salt of oxalic acid MONSANTO COMPANY (US) 1995-08-08 US disclosed
US-5271858-A Field dependent fluids containing electrically conductive tin oxide coated materials ENSCI INC. (US) 1993-12-21 US disclosed
US-4151101-A SILICONE AND ALKANOLAMIDE STAUFFER CHEMICAL COMPANY (US) 1979-04-24 US disclosed
US-3957666-A HYDRAULIC FLUIDS, HEAT TRANSFER FLUIDS MONSANTO COMPANY (US) 1976-05-18 US disclosed