Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667749 | 0.81 | HTR2A (0.53) | CHRM3ALOX5MAOAMAOBHTR2A | |
| SCHEMBL6973661 | 0.78 | ALOX5 (0.39) | CHRM3ALOX5MAOAMAOBMEN1 | |
| SCHEMBL29556345 | 0.78 | ALOX5 (0.39) | CHRM3ALOX5MAOAMAOBMEN1 | |
| SCHEMBL11994185 | 0.78 | ALOX5 (0.35) | CHRM3ALOX5MAOAMAOBHTR2A | |
| SCHEMBL9091614 | 0.77 | AKR1B1 (0.47) | CHRM3ALOX5MEN1KMT2AUSP2 | |
| SCHEMBL7509522 | 0.76 | ALOX5 (0.34) | CHRM3ALOX5MAOAMAOBHTR2A | |
| SCHEMBL10083663 | 0.76 | ELANE (0.43) | CHRM3ALOX5MAOAMAOBHTR2A | |
| SCHEMBL13672457 | 0.76 | CHRM3 (0.45) | CHRM3ALOX5MAOAMAOBMEN1 | |
| SCHEMBL29360424 | 0.75 | ALOX5 (0.44) | CHRM3ALOX5MAOAMAOBHTR2A | |
| SCHEMBL47009 | 0.75 | ALOX5 (0.44) | CHRM3ALOX5MAOAMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098453-A1 | AZONIA BICYCLOALKANES AS M3 MUSCARINIC ACETYLCHOLIN RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | WO | disclosed |