SCHEMBL402639

SCHEMBL402639

CC(=O)OC1COC(CO)[C@@H](O)[C@H]1OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.60
BCHE P06276 3/20 0.46
LGALS8 O00214 1/20 0.43
METAP2 P50579 2/20 0.41
PDE4D Q08499 1/20 0.40
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 1/20 0.38
TACR2 P21452 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19145004 0.86 SLC6A2 (0.69) SLC6A2BCHELGALS8PDE4D
SCHEMBL402884 0.85 BCHE (0.47) SLC6A2BCHEMETAP2POLBGAA
SCHEMBL19980839 0.82 BCHE (0.47) SLC6A2BCHETACR2
SCHEMBL14478933 0.82 BCHE (0.47) SLC6A2BCHEMETAP2POLBGAA
SCHEMBL403707 0.82 BCHE (0.45) SLC6A2BCHEMETAP2POLBGAA
SCHEMBL404009 0.82 BCHE (0.47) SLC6A2BCHEMETAP2POLBGAA
SCHEMBL404173 0.81 SLC6A2 (0.59) SLC6A2BCHELGALS8PDE4D
SCHEMBL19976424 0.81 TSHR (0.51) SLC6A2BCHEPOLBGAAALDH1A1
SCHEMBL22965651 0.80 BCHE (0.48) BCHEMETAP2POLBGAAALDH1A1
SCHEMBL12516420 0.80 SLC6A2 (0.62) SLC6A2BCHEPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120065153-A1 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF SANOFI-AVENTIS (FR) 2012-03-15 US disclosed
US-20070270354-A1 Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof SANOFI-AVENTIS (FR) 2007-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065153-A1 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF HPSE, HAAO, HEXD SLC6A2 2728/4885BCHE 1419/4885LGALS8 836/4885
US-20070270354-A1 Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof HPSE, HAAO, HEXD SLC6A2 2759/4885BCHE 1409/4885LGALS8 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.