Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3607520 | 0.87 | HTR6 (0.48) | HTR6DRD2HTR2ADRD3 | |
| SCHEMBL3618330 | 0.80 | HTR6 (0.55) | HTR6DRD2HTR2ADRD3 | |
| SCHEMBL3620801 | 0.78 | HTR6 (0.66) | HTR6DRD2HTR2ADRD3 | |
| Trifluoroacetic Acid SCHEMBL4021326 | 0.78 | HTR6 (0.43) | HTR6DRD2HTR2ADRD3BCHE | |
| SCHEMBL9590277 | 0.69 | HTR6 (0.66) | HTR6 | |
| Trifluoroacetic Acid SCHEMBL3620057 | 0.65 | HTR6 (0.53) | HTR6DRD2HTR2ADRD3BCHE | |
| SCHEMBL4680178 | 0.64 | HTR6 (0.73) | HTR6DRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL1999647 | 0.63 | HTR6 (0.40) | HTR6DRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL3616512 | 0.63 | HTR6 (0.64) | HTR6DRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL4020079 | 0.62 | HTR6 (0.55) | HTR6DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046741-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (publ) (SE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008003703-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2008-01-10 | — | — | WO | disclosed |