Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3949120 | 0.98 | APLNR (0.42) | APLNR | |
| SCHEMBL31471324 | 0.90 | APLNR (0.41) | APLNR | |
| SCHEMBL1440344 | 0.85 | APLNR (0.45) | APLNRHRH1KCNH2TRPV3 | |
| SCHEMBL1440342 | 0.85 | APLNR (0.45) | APLNRHRH1KCNH2TRPV3 | |
| Hydrochloric Acid SCHEMBL1693505 | 0.84 | APLNR (0.44) | APLNRHRH1KCNH2TRPV3 | |
| Hydrochloric Acid SCHEMBL1439641 | 0.84 | APLNR (0.44) | APLNRHRH1KCNH2TRPV3 | |
| Hydrochloric Acid SCHEMBL1438841 | 0.84 | APLNR (0.44) | APLNRHRH1KCNH2TRPV3 | |
| Hydrochloric Acid SCHEMBL3020024 | 0.84 | APLNR (0.44) | APLNRHRH1KCNH2TRPV3 | |
| Hydrochloric Acid SCHEMBL1693507 | 0.84 | APLNR (0.44) | APLNRHRH1KCNH2TRPV3 | |
| SCHEMBL20472734 | 0.79 | MAOB (0.38) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095712-A2 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-06 | — | — | WO | disclosed |