SCHEMBL4027201

SCHEMBL4027201

Cc1cn(C)cc1OC(=O)Nc1ccccc1-c1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 11/20 0.49
CHRM2 P08172 1/20 0.45
CHRM1 P11229 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 1/20 0.42
ATM Q13315 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
LMNA P02545 1/20 0.41
PLA2G1B P04054 1/20 0.41
THRB P10828 1/20 0.41
NPY1R P25929 1/20 0.41
NPY2R P49146 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4023977 0.88 CHRM3 (0.50) CHRM3SMN1; SMN2LMNASLC6A4SLC6A3
SCHEMBL4026463 0.88 CHRM3 (0.52) CHRM3CHRM1MEN1KMT2ATDP1
SCHEMBL4030355 0.88 CHRM3 (0.52) CHRM3CHRM2CHRM1MEN1KMT2A
SCHEMBL4027611 0.86 CHRM3 (0.47) CHRM3MEN1KMT2AATMSMN1; SMN2
SCHEMBL4033730 0.85 CHRM3 (0.52) CHRM3
SCHEMBL4026961 0.84 CHRM3 (0.48) CHRM3CHRM2CHRM1MEN1KMT2A
SCHEMBL4031163 0.84 CHRM3 (0.46) CHRM3CHRM2CHRM1MEN1KMT2A
SCHEMBL4028195 0.84 CHRM3 (0.53) CHRM3CHRM2CHRM1
SCHEMBL4031383 0.81 CHRM3 (0.48) CHRM3MEN1KMT2ATDP1ATM
SCHEMBL4027799 0.81 CHRM3 (0.52) CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252140-B1 PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-05-13 EP claimed