Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 2/20 | 0.41 |
| ▸ | NPY2R | P49146 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028003 | 0.90 | CHRM3 (0.48) | CHRM3CHRM2CHRM1LMNAL3MBTL1 | |
| SCHEMBL5710621 | 0.89 | LMNA (0.40) | CHRM3LMNANPSR1L3MBTL1SLC6A3 | |
| SCHEMBL4025520 | 0.89 | CHRM3 (0.49) | CHRM3CHRM2CHRM1MEN1KMT2A | |
| SCHEMBL4024951 | 0.87 | CHRM3 (0.44) | CHRM3CHRM2CHRM1MEN1KMT2A | |
| SCHEMBL4027201 | 0.84 | CHRM3 (0.49) | CHRM3CHRM2CHRM1NPY1RNPY2R | |
| SCHEMBL4025589 | 0.84 | CHRM3 (0.46) | CHRM3SMN1; SMN2NPSR1KMT2ATDP1 | |
| SCHEMBL4027584 | 0.83 | CHRM3 (0.50) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4026961 | 0.83 | CHRM3 (0.48) | CHRM3CHRM2CHRM1NPSR1MEN1 | |
| SCHEMBL4031806 | 0.82 | CHRM3 (0.41) | CHRM3CHRM2CHRM1MEN1KMT2A | |
| SCHEMBL4028195 | 0.81 | CHRM3 (0.53) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |