Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027364 | 1.00 | NAAA (0.39) | NAAAL3MBTL1EPHX1CYP19A1MAPK13 | |
| SCHEMBL4031737 | 1.00 | NAAA (0.39) | NAAAL3MBTL1EPHX1CYP19A1MAPK13 | |
| SCHEMBL15543405 | 0.89 | MAPK13 (0.39) | NAAAL3MBTL1EPHX1CYP19A1MAPK13 | |
| SCHEMBL18075110 | 0.85 | EPHX1 (0.39) | NAAAL3MBTL1EPHX1CYP19A1MAPK13 | |
| SCHEMBL18075109 | 0.85 | EPHX1 (0.39) | NAAAL3MBTL1EPHX1CYP19A1MAPK13 | |
| SCHEMBL3344777 | 0.84 | NAAA (0.39) | NAAAL3MBTL1EPHX1CYP19A1MAPK13 | |
| SCHEMBL19723190 | 0.84 | NAAA (0.45) | NAAAL3MBTL1EPHX1CYP19A1MAPK13 | |
| SCHEMBL28510618 | 0.84 | NAAA (0.45) | NAAAL3MBTL1EPHX1CYP19A1MAPK13 | |
| SCHEMBL16086118 | 0.83 | EPHX1 (0.42) | NAAAL3MBTL1EPHX1CYP19A1CYP2C19 | |
| SCHEMBL15359992 | 0.83 | EPHX1 (0.42) | NAAAL3MBTL1EPHX1CYP19A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203711-A1 | Inhibitors of P38 Map Kinase | CHROMA THERAPEUTICS LTD. (GB) | 2009-08-13 | — | — | US | disclosed |
| EP-2016055-A1 | INHIBITORS OF P38 MAP KINASE | Chroma Therapeutics Limited (GB) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007129036-A1 | INHIBITORS OF P38 MAP KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203711-A1 | Inhibitors of P38 Map Kinase | MAPK1, MAPK3, CNKSR1 | NAAA 2196/4885L3MBTL1 712/4885EPHX1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.