Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034151 | 0.87 | CYP3A4 (0.38) | SIRT2 | |
| SCHEMBL4026392 | 0.82 | — | — | |
| SCHEMBL4029943 | 0.81 | SIRT2 (0.36) | NMBRSIRT2 | |
| SCHEMBL4028289 | 0.79 | CYP17A1 (0.46) | — | |
| SCHEMBL4033872 | 0.79 | CYP17A1 (0.33) | — | |
| SCHEMBL4027429 | 0.78 | ACSS2 (0.36) | SIRT2 | |
| SCHEMBL4026834 | 0.78 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL4026461 | 0.78 | CYP17A1 (0.41) | SIRT2 | |
| SCHEMBL4028297 | 0.78 | SIRT2 (0.35) | NMBRSIRT2 | |
| SCHEMBL7533088 | 0.78 | CYP17A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222174-B1 | IMIDAZOL-4-YLMETHANOLS USED AS INHIBITORS OF STEROID C17-20 LYASE | TAKEDA PHARMACEUTICAL (JP) | 2009-05-27 | — | — | EP | disclosed |
| US-6649643-B1 | Antitumor, anticarcinogenic, and antimetastasis agents; benign prostatic hyperplasia, alopecia, endometriosis, uterine myoma, hirsutism, virilism, precocious puberty, mastopathy, and polycystic overay syndrome treatment | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-18 | — | — | US | disclosed |
| EP-1222174-A1 | IMIDAZOL-4-YLMETHANOLS USED AS INHIBITORS OF STEROID C17-20 LYASE | Takeda Chemical Industries, Ltd. (JP) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001030762-A1 | IMIDAZOL-4-YLMETHANOLS USE AS INHIBITORS OF STEROID C17-20 LYASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |