Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 13/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033206 | 0.94 | SLC9A3 (0.47) | SLC9A3TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4028349 | 0.93 | SLC9A3 (0.46) | SLC9A3 | |
| SCHEMBL4031999 | 0.91 | SLC9A3 (0.45) | SLC9A3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5749556 | 0.85 | SLC9A3 (0.49) | SLC9A3 | |
| SCHEMBL4025313 | 0.85 | SLC9A3 (0.45) | SLC9A3 | |
| Cyclopentane SCHEMBL4034441 | 0.85 | SLC9A3 (0.51) | SLC9A3 | |
| SCHEMBL4027298 | 0.85 | SLC9A3 (0.49) | SLC9A3 | |
| SCHEMBL4035908 | 0.85 | SLC9A3 (0.51) | SLC9A3 | |
| Cyclopropane SCHEMBL4031343 | 0.85 | SLC9A3 (0.51) | SLC9A3 | |
| SCHEMBL4027266 | 0.84 | SLC9A3 (0.48) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453810-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-1453810-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-18 | — | — | EP | disclosed |