Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 13/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033206 | 0.99 | SLC9A3 (0.47) | SLC9A3MAPTPKMMAPK1 | |
| SCHEMBL4027669 | 0.93 | SLC9A3 (0.47) | SLC9A3 | |
| SCHEMBL4031999 | 0.90 | SLC9A3 (0.45) | SLC9A3MAPT | |
| Cyclopropane SCHEMBL4031343 | 0.88 | SLC9A3 (0.51) | SLC9A3 | |
| SCHEMBL4035908 | 0.88 | SLC9A3 (0.51) | SLC9A3 | |
| Cyclopentane SCHEMBL4034441 | 0.88 | SLC9A3 (0.51) | SLC9A3 | |
| SCHEMBL4031741 | 0.86 | SLC9A3 (0.44) | SLC9A3 | |
| SCHEMBL5749556 | 0.85 | SLC9A3 (0.49) | SLC9A3 | |
| SCHEMBL4029110 | 0.85 | SLC9A3 (0.45) | SLC9A3 | |
| SCHEMBL4027298 | 0.84 | SLC9A3 (0.49) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453810-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-1453810-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-18 | — | — | EP | disclosed |