Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.66 |
| ▸ | TACR3 | P29371 | 2/20 | 0.66 |
| ▸ | TACR2 | P21452 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4021098 | 0.99 | TACR1 (0.65) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL4021064 | 0.86 | TACR1 (0.61) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL4023089 | 0.86 | TACR1 (0.61) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL4021070 | 0.86 | TACR1 (0.58) | TACR1TACR3TACR2CYP3A4 | |
| Hydrochloric Acid SCHEMBL4023056 | 0.85 | TACR1 (0.57) | TACR1TACR3TACR2CYP3A4 | |
| SCHEMBL4021312 | 0.80 | TACR1 (0.62) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL9277010 | 0.79 | TACR1 (1.00) | TACR1TACR3TACR2 | |
| SCHEMBL29373930 | 0.79 | TACR1 (1.00) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL6228761 | 0.79 | TACR1 (1.00) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL29374556 | 0.79 | TACR1 (1.00) | TACR1TACR3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1338592-B1 | Novel 2-phenylpiperazine derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2009-01-21 | — | — | EP | claimed |