Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187651 | 0.78 | LMNA (0.59) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL4028242 | 0.78 | PLA2G1B (0.48) | HPGDLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2186894 | 0.72 | LMNA (0.54) | HPGDLMNANPC1RAB9ACCNB2 | |
| SCHEMBL81774 | 0.70 | LMNA (0.45) | HPGDLMNACCNB2CCNE2CDK1 | |
| SCHEMBL20228172 | 0.69 | LMNA (0.48) | HPGDLMNANPC1RAB9ACCNB2 | |
| SCHEMBL2186250 | 0.67 | LMNA (0.60) | HPGDLMNAALDH1A1KMT2A | |
| SCHEMBL81576 | 0.67 | LMNA (0.60) | HPGDLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL2187010 | 0.66 | LMNA (0.59) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL18233757 | 0.65 | PTPN1 (0.48) | HPGDLMNAHDAC6 | |
| SCHEMBL2187912 | 0.65 | MAPT (0.58) | HPGDLMNARAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550463-B2 | Carbamoylpyridone derivatives having inhibitory activity against HIV integrase | SHIONOGI & CO., LTD. (JP) | 2009-06-23 | — | — | US | disclosed |
| US-20070249687-A1 | Carbamoylpyridone Derivatives Having Inhibitory Activity Against Hiv Integrase | SHIONOGI & CO., LTD. (JP) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249687-A1 | Carbamoylpyridone Derivatives Having Inhibitory Activity Against Hiv Integrase | CDKL4, CDKL5, CDKL1 | PDE4D 4015/4885HPGD 4103/4885LMNA 4066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.